MUC4 抗体 (AA 1730-1864) (CF®640R)
Quick Overview for MUC4 抗体 (AA 1730-1864) (CF®640R) (ABIN7657398)
抗原
See all MUC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1730-1864
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原理
- MUC4 (Mucin 4 / Gastric Mucin)(MUC4/3105), CF640R conjugate
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产品特性
- The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 1730-1864) of human MUC4 protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Stomach, Colon or esophagus.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MUC4 (Mucin 4, Cell Surface Associated (MUC4))
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别名
- MUC4
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背景
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Synonyms: Ascites sialoglycoprotein 1, Ascites sialoglycoprotein 2, Ascites sialoglycoprotein, ASGP, ASGP-1, ASGP-2, Mucin 4 cell surface associated, Mucin-4 beta chain, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin
Gene Symbol: MUC4
Tissue Expression: Epithelial cells
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分子量
- 235 kDa
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基因ID
- 4585
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UniProt
- Q99102
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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