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Moesin 抗体 (CF®488A)

This anti-Moesin antibody is a 小鼠 单克隆 antibody detecting Moesin in WB, IHC, IF, FACS 和 IHC (fp). Suitable for 人 和 大鼠.
产品编号 ABIN7657228
发货至: 中国

Quick Overview for Moesin 抗体 (CF®488A) (ABIN7657228)

抗原

See all Moesin (MSN) 抗体
Moesin (MSN)

适用

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人, 大鼠

宿主

  • 68
  • 46
  • 1
小鼠

克隆类型

  • 59
  • 55
单克隆

标记

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  • 1
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This Moesin antibody is conjugated to CF®488A

应用范围

  • 97
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

MSN-491
  • 原理

    Moesin(MSN/491), CF488A conjugate

    产品特性

    Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human Moesin protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: K562, HT-29, CH3LC or HUVEC cells. Uterus, Placenta, Tonsil, Melanoma, Testicular Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Moesin (MSN)

    别名

    Moesin

    背景

    Synonyms: Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSLK fusion

    Gene Symbol: MSN

    分子量

    78 kDa

    基因ID

    4478

    UniProt

    P26038

    途径

    Asymmetric Protein Localization
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