Recombinant MTAP 抗体 (AA 97-196) (CF®405S)
Quick Overview for Recombinant MTAP 抗体 (AA 97-196) (CF®405S) (ABIN7657023)
抗原
See all MTAP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 97-196
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原理
- MTAP (Tumor Suppressor Marker)(rMTAP/1813), CF405S conjugate
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产品特性
- Recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e. g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human MTAP protein fragment (aa97-196)
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亚型
- IgG1, kappa
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anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-154) antibody
MTAP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) antibodyMTAP 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal MTAP-3137R unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal MTAP-1813 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal rMTAP-1813 unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) (Internal Region) antibodyMTAP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 8-37), (N-Term) antibodyMTAP 适用: 人 WB 宿主: 兔 Polyclonal RB42759 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HepG2, A431, HeLa or MCF-7 cells. Human kidney tissues (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MTAP (Methylthioadenosine phosphorylase (MTAP))
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别名
- MTAP
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背景
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Synonyms: BDMF, DMSFH, DMSMFH, Epididymis luminal protein 249, HEL249, LGMBF, MeSAdo phosphorylase, Methylthioadenosine phosphorylase, MSAP, MTA phosphorylase, MTAPase, S-methyl-5''-thioadenosine phosphorylase
Gene Symbol: MTAP
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分子量
- 31 kDa
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基因ID
- 4507
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UniProt
- Q13126
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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