MTF1 抗体 (CF®488A)
Quick Overview for MTF1 抗体 (CF®488A) (ABIN7656974)
抗原
See all MTF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MTF1(MTF1/2649), CF488A conjugate
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产品特性
- The metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human MTF1 protein
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亚型
- IgG1, kappa
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anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 2-139) antibody
MTF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 41-140) antibodyMTF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) antibodyMTF1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MTF1-2649 unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 101-200) antibodyMTF1 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 562-611) antibodyMTF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 2-164) antibodyMTF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Human kidney.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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别名
- MTF1
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背景
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Synonyms: Metal regulatory transcription factor 1, Metal response element binding transcription factor 1, Metal responsive transcription factor 1, MRE-binding transcription factor 1, MTF1, Transcription factor MTF1, Zinc regulatory factor (ZRF)
Gene Symbol: MTF1
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分子量
- 70 kDa
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基因ID
- 4520
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UniProt
- Q14872
抗原
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