MTF1 抗体 (CF®405S)
Quick Overview for MTF1 抗体 (CF®405S) (ABIN7656969)
抗原
See all MTF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- MTF1(MTF1/2649), CF405S conjugate
-
产品特性
- The metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Recombinant full-length human MTF1 protein
-
亚型
- IgG1, kappa
-
-
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 2-139) antibody
MTF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 41-140) antibodyMTF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) antibodyMTF1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MTF1-2649 unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 101-200) antibodyMTF1 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 562-611) antibodyMTF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 2-164) antibodyMTF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Positive Control: Human kidney.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Protect from light
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
-
别名
- MTF1
-
背景
-
Synonyms: Metal regulatory transcription factor 1, Metal response element binding transcription factor 1, Metal responsive transcription factor 1, MRE-binding transcription factor 1, MTF1, Transcription factor MTF1, Zinc regulatory factor (ZRF)
Gene Symbol: MTF1
-
分子量
- 70 kDa
-
基因ID
- 4520
-
UniProt
- Q14872
抗原
-
