MMP3 抗体 (AA 317-327) (CF®488A)
Quick Overview for MMP3 抗体 (AA 317-327) (CF®488A) (ABIN7656636)
抗原
See all MMP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 317-327
-
原理
- MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(1B4), CF488A conjugate
-
产品特性
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Recombinant fragment corresponding to amino acids 317-327 of human MMP3.
-
亚型
- IgG1, kappa
-
-
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 248-477) antibody
MMP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 363-477) antibodyMMP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 278-450) antibodyMMP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 1-477) antibodyMMP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibodyMMP3 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 401-477) antibodyMMP3 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 100-477) antibodyMMP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 22-131) antibodyMMP3 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (C-Term) antibodyMMP3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibodyMMP3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F10 unconjugated
-
-
应用备注
- ELISA: Use at 2-4 μg/mL for coating, Order without BSA, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
-
说明
-
Positive Control: A431 cells. Prostate or Lung Carcinoma.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Protect from light
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
-
别名
- MMP3
-
背景
-
Synonyms: CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, MMP3, Proteoglycanase, SL1, STMY1, STR1, Stromelysin-1, Transin 1
Gene Symbol: MMP3
-
分子量
- 57 kDa
-
基因ID
- 4314
-
UniProt
- P08254
抗原
-
