LI Cadherin 抗体 (AA 242-418) (CF®405S)
Quick Overview for LI Cadherin 抗体 (AA 242-418) (CF®405S) (ABIN7656331)
抗原
See all LI Cadherin 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 242-418
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原理
- Cadherin 17 / LI Cadherin (Liver-Intestine Marker)(CDH17/2617), CF405S conjugate
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产品特性
- Cadherin 17, also known as LI cadherin (for liver-intestine cadherin), is a member of the cadherin family of calcium-dependent adhesion molecules. Cadherins mediate cell-cell interactions via hemophilic binding, and are critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. Cadherin 17 expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17)
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亚型
- IgG2b, kappa
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anti-LI Cadherin (AA 242-418) antibody
适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-517M unconjugated
anti-LI Cadherin antibody适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (AA 24-131) antibody适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-LI Cadherin antibody适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-LI Cadherin (AA 600-707) antibody适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 7D10E1 unconjugated
anti-LI Cadherin (AA 67-351) antibody适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (AA 242-418) antibody适用: 人 FACS, IHC (f) 宿主: 小鼠 Monoclonal CDH17-2618 unconjugated
anti-LI Cadherin (AA 101-200) antibody适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (Internal Region) antibody适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (AA 242-418) antibody适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal CDH17-2617 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- LI Cadherin
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别名
- Cadherin 17
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背景
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Synonyms: Cadherin 17, Cadherin-17, CDH17, LI-cadherin, Liver-intestine cadherin, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1
Gene Symbol: CDH17
Tissue Expression: Intestine|Liver
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分子量
- 120 kDa
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基因ID
- 1015
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UniProt
- Q12864
抗原
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