LGALS13 抗体 (AA 23-134) (CF®740)
Quick Overview for LGALS13 抗体 (AA 23-134) (CF®740) (ABIN7656328)
抗原
See all LGALS13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
- 
    
- 
                                            
抗原表位
 - AA 23-134
 - 
                                            
原理
 - Galectin-13 (GAL13) / Placental Protein 13 (PP13) (PP13/1165), CF740 conjugate
 - 
                                            
产品特性
 - This antibody recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
 - 
                                            
免疫原
 - Recombinant human Galectin-13 protein fragment (aa23-134)
 - 
                                            
亚型
 - IgG2b
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology (formalin): 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 or 10 mM citrate buffer pH 6.0 for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. ELISA For coating, order Ab without BSA. Optimal dilution for a specific application should be determined by user
 - 
                                            
说明
 - 
                        
Positive Control: K-562 cells. Placenta or Spleen.
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
浓度
 - 0.1 mg/mL
 - 
                                            
缓冲液
 - PBS, 0.1 % rBSA, 0.05 % azide
 - 
                                            
储存液
 - Sodium azide
 - 
                                            
注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 - 
                                            
注意事项
 - Protect from light
 - 
                                            
储存条件
 - 4 °C
 - 
                                            
储存方法
 - 
                        
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
 - 
                                            
有效期
 - 24 months
 
 - 
                                            
 - 
    
- LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
 - 
                                            
别名
 - Galectin-13
 - 
                                            
背景
 - 
                        
Synonyms: Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13
Gene Symbol: LGALS13
 - 
                                            
分子量
 - 16 kDa (monomer), 32 kDa (homodimer)
 - 
                                            
基因ID
 - 29124
 - 
                                            
UniProt
 - Q9UHV8
 
抗原
 -