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LGALS13 抗体 (AA 23-134) (CF®740)

This anti-LGALS13 antibody is a 小鼠 单克隆 antibody detecting LGALS13 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7656327
发货至: 中国

Quick Overview for LGALS13 抗体 (AA 23-134) (CF®740) (ABIN7656327)

抗原

See all LGALS13 抗体
LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

适用

  • 32
  • 1

宿主

  • 25
  • 7
小鼠

克隆类型

  • 23
  • 9
单克隆

标记

  • 15
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This LGALS13 antibody is conjugated to CF®740

应用范围

  • 26
  • 21
  • 16
  • 16
  • 12
  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

PP13-1164
  • 抗原表位

    • 21
    • 5
    • 1
    • 1
    • 1
    AA 23-134

    原理

    Galectin-13 (GAL13) / Placental Protein 13 (PP13) (PP13/1164), CF740 conjugate

    产品特性

    This antibody recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human Galectin-13 protein fragment (aa23-134)

    亚型

    IgG2b
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology (formalin): 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 or 10 mM citrate buffer pH 6.0 for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. ELISA For coating, order Ab without BSA. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: K-562 cells. Placenta or Spleen.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

    别名

    Galectin-13

    背景

    Synonyms: Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13

    Gene Symbol: LGALS13

    分子量

    16 kDa (monomer), 32 kDa (homodimer)

    基因ID

    29124

    UniProt

    Q9UHV8
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