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Recombinant KRT6A 抗体

This anti-KRT6A antibody is a 小鼠 单克隆 antibody detecting KRT6A in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7656219
发货至: 中国

Quick Overview for Recombinant KRT6A 抗体 (ABIN7656219)

抗原

See all KRT6A 抗体
KRT6A (Keratin 6A (KRT6A))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This KRT6A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

RKRT6A-2100
  • 原理

    Cytokeratin 6A (KRT6A) (Basal Cell Marker)(rKRT6A/2100)

    产品特性

    This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human Cytokeratin 6A (KRT6A) protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Tonsil or basal cell carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, no BSA, no azide

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at -20 °C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    KRT6A (Keratin 6A (KRT6A))

    别名

    Keratin 6A

    背景

    Synonyms: 58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5

    Gene Symbol: KRT6A

    Tissue Expression: Epidermal cells

    分子量

    58 kDa

    基因ID

    3853

    UniProt

    P02538
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