KRT6A 抗体 (CF®488A)
Quick Overview for KRT6A 抗体 (CF®488A) (ABIN7656210)
抗原
See all KRT6A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), CF488A conjugate
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产品特性
- This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human Cytokeratin 6A (KRT6A) protein
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亚型
- IgG2a, kappa
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anti-Keratin 6A (KRT6A) (AA 163-468) antibody
KRT6A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal KRT6A-2368 unconjugated
anti-Keratin 6A (KRT6A) (AA 253-352) antibodyKRT6A 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7E3D1 unconjugated
anti-Keratin 6A (KRT6A) (AA 2-564) antibodyKRT6A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) (AA 163-468) antibodyKRT6A 适用: 人 WB 宿主: 小鼠 Monoclonal D9 unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) (AA 305-564) antibodyKRT6A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rKRT6A-2100 unconjugated Recombinant Antibody
anti-Keratin 6A (KRT6A) (N-Term) antibodyKRT6A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Tonsil or Basal Cell Carcinoma (BCC)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- KRT6A (Keratin 6A (KRT6A))
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别名
- Keratin 6A
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背景
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Synonyms: 58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5
Gene Symbol: KRT6A
Tissue Expression: Epidermal cells
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分子量
- 56 kDa
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基因ID
- 3853
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UniProt
- P02538
抗原
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