KRT17 抗体 (CF®740)
Quick Overview for KRT17 抗体 (CF®740) (ABIN7656021)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Cytokeratin 17(KRT17/778), CF740 conjugate
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产品特性
- Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human KRT17 protein
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亚型
- IgG2b, kappa
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anti-Keratin 17 (KRT17) antibody
KRT17 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 252-393) antibodyKRT17 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (AA 1-432) antibodyKRT17 适用: 人 WB, IF, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2D4-1G9 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠 WB, IHC, FACS, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal E3 unconjugated
anti-Keratin 17 (KRT17) (AA 133-432) antibodyKRT17 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, Cow, Pig, 山羊 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SPM560 unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) (C-Term) antibodyKRT17 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 17 (KRT17) antibodyKRT17 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Keratin 17 (KRT17) (C-Term) antibodyKRT17 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 兔, 绵羊, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: T24 cells or Skin. Bladder or Cervix.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- KRT17 (Keratin 17 (KRT17))
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别名
- Keratin 17
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背景
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Synonyms: K17, Keratin Type I Cytoskeletal 17, Keratin-17, KRT17, PCHC1
Gene Symbol: KRT17
Tissue Expression: Epithelial cells
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分子量
- 46 kDa
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基因ID
- 3872
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UniProt
- Q04695
抗原
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