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Recombinant KRT16 抗体 (C-Term) (Biotin)

This anti-KRT16 antibody is a 兔 单克隆 antibody detecting KRT16 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7656010
发货至: 中国

Quick Overview for Recombinant KRT16 抗体 (C-Term) (Biotin) (ABIN7656010)

抗原

See all KRT16 抗体
KRT16 (Keratin 16 (KRT16))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This KRT16 antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

KRT16-2043R
  • 抗原表位

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    C-Term

    原理

    Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker) (KRT16/2043R), Biotin conjugate

    产品特性

    Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment from the C-terminal of human Cytokeratin 16

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: HeLa cells. Tonsil, Skin. Bladder, or Cervix.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    KRT16 (Keratin 16 (KRT16))

    别名

    Keratin 16

    背景

    Synonyms: CK16, Cytokeratin-16, Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK), K1CP, Keratin Type I Cytoskeletal 16, Keratin-16, KRT16A

    Gene Symbol: KRT16

    Tissue Expression: Epidermal cells

    分子量

    48 kDa

    基因ID

    3868

    UniProt

    P08779
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