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Cytokeratin 13 抗体 (CF®740)

This CF®740-conjugated 小鼠 单克隆 anti-Cytokeratin 13 antibody (Clone KRT13-2213) specifically detects Cytokeratin 13 in IHC, FACS 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7655910
发货至: 中国
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Quick Overview for Cytokeratin 13 抗体 (CF®740) (ABIN7655910)

抗原

See all Cytokeratin 13 (KRT13) 抗体
Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 13 antibody is conjugated to CF®740

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

KRT13-2213
  • 原理

    Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)(KRT13/2213), CF740 conjugate

    产品特性

    Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human KRT13 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa or A431 cells. Skin or Squamous cell carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

    别名

    Keratin 13

    背景

    Synonyms: CK13, Cytokeratin-13, Keratin Type I Cytoskeletal 13, Keratin-13, KRT13, Type I Cytoskeletal 13, WSN2

    Gene Symbol: KRT13

    Tissue Expression: Epidermal cells

    分子量

    52 kDa

    基因ID

    3860

    UniProt

    P13646
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