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Cytokeratin 1 抗体 (C-Term) (CF®594)

This anti-Cytokeratin 1 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 1 in IHC 和 IHC (fp). Suitable for 人 和 大鼠.
产品编号 ABIN7655842
发货至: 中国
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Quick Overview for Cytokeratin 1 抗体 (C-Term) (CF®594) (ABIN7655842)

抗原

See all Cytokeratin 1 (KRT1) 抗体
Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

适用

  • 109
  • 66
  • 61
  • 24
  • 16
  • 13
  • 8
  • 8
  • 7
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 86
  • 46
  • 1
小鼠

克隆类型

  • 69
  • 64
单克隆

标记

  • 53
  • 16
  • 8
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cytokeratin 1 antibody is conjugated to CF®594

应用范围

  • 93
  • 54
  • 53
  • 27
  • 27
  • 26
  • 24
  • 20
  • 17
  • 17
  • 16
  • 9
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

LHK1
  • 抗原表位

    • 20
    • 16
    • 16
    • 12
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Cytokeratin 1 (Suprabasal Keratinocyte Marker)(LHK1), CF594 conjugate

    产品特性

    Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Skin or Cervix.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

    别名

    Keratin 1

    背景

    Synonyms: 67 kDa Cytokeratin, CK1, Cytokeratin-1, EHK1, Epidermolytic hyperkeratosis 1, EPPK, K1, Keratin Type II Cytoskeletal 1, Keratin-1, KRT1, KRT1A, NEPPK, Type II cytoskeletal 1, Type-II keratin Kb1

    Gene Symbol: KRT1

    Tissue Expression: Epithelial cells

    分子量

    67 kDa

    基因ID

    38748

    UniProt

    P04264
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