Iba1 抗体 (AA 1-146) (CF®488A)
Quick Overview for Iba1 抗体 (AA 1-146) (CF®488A) (ABIN7655782)
抗原
See all Iba1 (IBA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-146
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原理
- AIF1 / Iba1 (Microglia Marker)(AIF1/2493), CF488A conjugate
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产品特性
- Allograft Inflammatory Factor 1 (also known as AIF1 or IBA1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Purified recombinant human AIF1 protein (around aa 1-146)
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亚型
- IgG2c, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Lymph Node, Tonsil or Kidney
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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别名
- Allograft Inflammatory Factor 1
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背景
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Synonyms: Allograft inflammatory factor 1, AIF1, IBA1
Gene Symbol: AIF1
Tissue Expression: Microglia|Monocytes/macrophages
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分子量
- 17 kDa
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基因ID
- 199
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UniProt
- P55008
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途径
- Smooth Muscle Cell Migration
抗原
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