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IL3RA 抗体 (AA 26-171) (CF®568)

This anti-IL3RA antibody is a 小鼠 单克隆 antibody detecting IL3RA in . Suitable for 人.
产品编号 ABIN7655692
发货至: 中国

Quick Overview for IL3RA 抗体 (AA 26-171) (CF®568) (ABIN7655692)

抗原

See all IL3RA 抗体
IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

适用

  • 144
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宿主

  • 76
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小鼠

克隆类型

  • 98
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单克隆

标记

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This IL3RA antibody is conjugated to CF®568

应用范围

请咨询

克隆位点

IL3RA-2065
  • 抗原表位

    • 37
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    AA 26-171

    原理

    IL3RA / CD123 (Acute Myeloid Leukemia Marker) (IL3RA/2065), CF568 conjugate

    产品特性

    CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human IL3RA protein fragment (around aa 26-171)

    亚型

    IgG2a, kappa
  • 应用备注

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    别名

    CD123

    背景

    Synonyms: CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal

    Gene Symbol: IL3RA

    分子量

    70 kDa

    基因ID

    3563

    UniProt

    P26951

    途径

    JAK/STAT Signaling
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