IL-10RA 抗体 (CF®594)
Quick Overview for IL-10RA 抗体 (CF®594) (ABIN7655656)
抗原
See all IL-10RA (IL10RA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)(1B1.3a), CF594 conjugate
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产品特性
- This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Purified recombinant extracellular region of Mouse IL10RA
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: MPBMC . Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- IL-10R1
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背景
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Synonyms: CD210 antigen, CDw210a, IBD28, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1
Tissue Expression: Lymphocytes|Monocytes/macrophages|NK cells
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分子量
- 90-110 kDa
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基因ID
- 16154
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UniProt
- Q61727
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途径
- Growth Factor Binding
抗原
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