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IL-10RA 抗体 (CF®647)

This CF®647-conjugated 大鼠 单克隆 anti-IL-10RA antibody (Clone 1B1-3a) specifically detects IL-10RA in FACS 和 Func. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7655652
发货至: 中国
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Quick Overview for IL-10RA 抗体 (CF®647) (ABIN7655652)

抗原

See all IL-10RA (IL10RA) 抗体
IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

适用

  • 86
  • 47
  • 18
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  • 1
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  • 1
小鼠

宿主

  • 78
  • 21
  • 12
  • 2
大鼠

克隆类型

  • 78
  • 33
  • 1
单克隆

标记

  • 63
  • 10
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  • 4
  • 4
  • 2
  • 1
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  • 1
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This IL-10RA antibody is conjugated to CF®647

应用范围

  • 73
  • 38
  • 28
  • 15
  • 14
  • 9
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

1B1-3a
  • 原理

    IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)(1B1.3a), CF647 conjugate

    产品特性

    This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Purified recombinant extracellular region of Mouse IL10RA

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: MPBMC . Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    别名

    IL-10R1

    背景

    Synonyms: CD210 antigen, CDw210a, IBD28, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1

    Tissue Expression: Lymphocytes|Monocytes/macrophages|NK cells

    分子量

    90-110 kDa

    基因ID

    16154

    UniProt

    Q61727

    途径

    Growth Factor Binding
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