IFNA2 抗体 (CF®405S)
Quick Overview for IFNA2 抗体 (CF®405S) (ABIN7655629)
抗原
See all IFNA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Interferon alpha-2 (IFNA2)(N39), CF405S conjugate
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产品特性
- This antibody recognizes a protein of 16-27 kDa, identified as human interferon-alpha-2 (IFN-a2). Its epitope maps between aa112-148 of IFN-a2 (total aa172). This MAb is specific for IFN-a2 and does not cross-react with interferon-alpha-1. The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-a2. Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-a2 after viral infections. The IFN-a family consists of 24 or more genes or pseudo-genes. IFN-a2 is one of the two distinct families (I and II) of human IFN-a. The alpha-interferons are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
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免疫原
- Purified recombinant human IFN-alpha2
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亚型
- IgG1, kappa
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anti-Interferon, alpha 2 (IFNA2) (AA 24-188) antibody
IFNA2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) (AA 24-188) antibodyIFNA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) (C-Term) antibodyIFNA2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) (AA 1-188) antibodyIFNA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) (AA 24-188) antibodyIFNA2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2B1 unconjugated
anti-Interferon, alpha 2 (IFNA2) (AA 24-188) antibodyIFNA2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Interferon, alpha 2 (IFNA2) (N-Term) antibodyIFNA2 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) (AA 24-192) antibodyIFNA2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) antibodyIFNA2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 2 (IFNA2) (AA 24-188) antibodyIFNA2 适用: 人 WB 宿主: 小鼠 Monoclonal D4 unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Stimulated human peripheral blood mononuclear cells
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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别名
- Interferon Alpha-2
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背景
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Synonyms: Alpha 2a interferon, IFN alpha, IFN-alpha-2, IFNA, IFNA2, IFNA2B, Interferon alpha 2a, Interferon alpha 2b, Interferon alpha-2, Interferon alpha-A, LeIF2, LeIFA
Gene Symbol: IFNA2
Tissue Expression: Lymphocytes|Monocytes/macrophages
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分子量
- 16-27 kDa
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基因ID
- 3440
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UniProt
- P01563
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
抗原
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