IFNA1 抗体 (CF®740)
Quick Overview for IFNA1 抗体 (CF®740) (ABIN7655622)
抗原
See all IFNA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Interferon alpha-1 (IFNA1)(2-48), CF740 conjugate
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产品特性
- This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
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免疫原
- Purified recombinant human IFN-alpha1
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亚型
- IgG1, kappa
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anti-Interferon, alpha 1 (IFNA1) (AA 24-133) antibody
IFNA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 150-189) antibodyIFNA1 适用: 小鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 24-189) antibodyIFNA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 1-189) antibodyIFNA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 25-155) antibodyIFNA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 164-189), (C-Term) antibodyIFNA1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21762 unconjugated
anti-Interferon, alpha 1 (IFNA1) (C-Term) antibodyIFNA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) antibodyIFNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 24-133) antibodyIFNA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon, alpha 1 (IFNA1) (AA 1-189) antibodyIFNA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Stimulated human peripheral blood mononuclear cells
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- IFNA1 (Interferon, alpha 1 (IFNA1))
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别名
- Interferon Alpha-1
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背景
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Synonyms: IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D
Gene Symbol: IFNA1
Tissue Expression: Lymphocytes|Monocytes/macrophages
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分子量
- 16-27 kDa
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基因ID
- 3439
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UniProt
- P01562
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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