ICAM-3/CD50 抗体
Quick Overview for ICAM-3/CD50 抗体 (ABIN7655584)
抗原
See all ICAM-3/CD50 (ICAM3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD50 / ICAM3(ICO-60)
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产品特性
- Recognizes the N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
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免疫原
- Human ICAM3
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亚型
- IgG1, kappa
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Flow cytometry: 0.5-1 μg/million cells. Immunofluorescence: 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HL-60 or THP-1 cells. Lymph node and tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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别名
- CD50
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背景
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Synonyms: ICAMR, Intercellular adhesion molecule 3 (ICAM3)
Gene Symbol: ICAM3
Tissue Expression: Lymphocytes|T-cells
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分子量
- 110-160 kDa
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基因ID
- 3385
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UniProt
- P32942
抗原
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