Recombinant ICAM-3/CD50 抗体
Quick Overview for Recombinant ICAM-3/CD50 抗体 (ABIN7655583)
抗原
See all ICAM-3/CD50 (ICAM3) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD50 / ICAM3(ICAM3/2873R)
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产品特性
- Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human ICAM3 protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HL-60 or THP-1 cells. Lymph node and tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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别名
- CD50
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背景
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Synonyms: CD50, CDW 50, CDw50, ICAM 3, ICAM-3, ICAM-R, ICAM3, ICAM3_HUMAN, ICAMR, Intercellular adhesion molecule 3
Gene Symbol: ICAM3
Tissue Expression: Lymphocytes|T-cells
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分子量
- 110-160 kDa
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基因ID
- 3385
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UniProt
- P32942
抗原
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