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Integrin beta 4 抗体 (CF®740)

This anti-Integrin beta 4 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 4 in FACS, IP, IF 和 Func. Suitable for 人.
产品编号 ABIN7655479
发货至: 中国

Quick Overview for Integrin beta 4 抗体 (CF®740) (ABIN7655479)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 4 antibody is conjugated to CF®740

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

UM-A9
  • 原理

    CD104(UM-A9), CF740 conjugate

    产品特性

    CD104 is beta 4 integrin. It is primarily expressed in epithelial cells. Together with alpha 6 integrin, it is the cell surface receptor for laminin, where it mediates cell adhesion. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human squamous cell carcinoma (UM-SCC1)

    亚型

    IgG2a, kappa
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Biological blockade partially blocks laminin binding. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: A431 cells, squamous cell carcinoma, colon or placenta

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    CD104

    背景

    Synonyms: CD104, Integrin beta 4, ITGB4, GP150

    Gene Symbol: ITGB4

    Tissue Expression: Epithelial cells

    分子量

    205 kDa

    基因ID

    3691

    UniProt

    P16144

    途径

    Integrin Complex
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