ITGB1 抗体
Quick Overview for ITGB1 抗体 (ABIN7655424)
抗原
See all ITGB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD29 (Stem Cell Marker)(12G10)
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产品特性
- Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.
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亚型
- IgG1, kappa
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应用备注
- Does not react with Mouse or Rat, ELISA: For coating use Ab at 1-5 μg/mL, order Ab without BSA, Optimal dilution for a specific application should be determined by user.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: HT1080 whole cell lysate. HeLa cell line.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- ITGB1 (Integrin beta 1 (ITGB1))
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别名
- CD29
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背景
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Synonyms: Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB
Gene Symbol: ITGB1
Tissue Expression: Platelets|Endothelial cells|Fibroblasts|Lymphocytes|Mast cells|Monocytes/macrophages|Smooth muscle
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分子量
- 110 kDa (non-reduced) & 130 kDa (reduced)
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基因ID
- 3688
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UniProt
- P05556
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途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
抗原
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