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ITGB1 抗体 (CF®568)

This anti-ITGB1 antibody is a 小鼠 单克隆 antibody detecting ITGB1 in FACS, IP, IF 和 Func. Suitable for 人.
产品编号 ABIN7655419
发货至: 中国

Quick Overview for ITGB1 抗体 (CF®568) (ABIN7655419)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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小鼠

克隆类型

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单克隆

标记

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This ITGB1 antibody is conjugated to CF®568

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

12G10
  • 原理

    CD29 (Stem Cell Marker)(12G10), CF568 conjugate

    产品特性

    Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.

    亚型

    IgG1, kappa
  • 应用备注

    Does not react with Mouse or Rat, ELISA: For coating use Ab at 1-5 μg/mL, order Ab without BSA, Optimal dilution for a specific application should be determined by user.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

    说明

    Positive Control: HT1080 whole cell lysate. HeLa cell line.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    CD29

    背景

    Synonyms: Fibrinogen Receptor beta subunit, FNRB, Glycoprotein IIa (GPIIA), Integrin beta-1 (ITGB1), integrin VLA-4 beta subunit, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLA-4 subunit beta, VLA-BETA, VLAB

    Gene Symbol: ITGB1

    Tissue Expression: Platelets|Endothelial cells|Fibroblasts|Lymphocytes|Mast cells|Monocytes/macrophages|Smooth muscle

    分子量

    110 kDa (non-reduced) & 130 kDa (reduced)

    基因ID

    3688

    UniProt

    P05556

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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