HIV-1 p24 抗体 (CF®740)
Quick Overview for HIV-1 p24 抗体 (CF®740) (ABIN7655163)
抗原
See all HIV-1 p24 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- p24-HIV(p24/661), CF740 conjugate
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产品特性
- Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4 T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant HIV-1 Gag p24 protein
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亚型
- IgG1, kappa
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anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 48-62) antibody
HIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB, IF 宿主: 小鼠 Monoclonal 5 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (full length) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB, IP, DB 宿主: 豚鼠 Polyclonal unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 80-90) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal 2N32 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 165-231), (C-Term) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal 2N44 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 74-84) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal 2N34 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 165-231), (C-Term) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal N13 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 1-104), (N-Term) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal N29 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) antibody (Biotin)HIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB, IF, IP 宿主: 兔 Polyclonal Biotin
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: HIV-1 infected cells or tissues.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))
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别名
- HIV p24
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物质类
- Viral Protein
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背景
- Capsid protein p24, Human immunodeficiency virus type 1 p24, HIV1gp1, HIV-1 Gag p24
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分子量
- 24 kDa (mature); 55 kDa & 41 kDa (precursors)
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基因ID
- 155348
抗原
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