HNF1A 抗体 (AA 214-339) (Biotin)
Quick Overview for HNF1A 抗体 (AA 214-339) (Biotin) (ABIN7655150)
抗原
See all HNF1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 214-339
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原理
- HNF1A (Pancreatic Tumor Suppressor)(HNF1A/2087), Biotin conjugate
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产品特性
- HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1Aas a susceptibility gene for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 214-339) of human HNF1A protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Jurkat cells. Small Intestine or Pancreas.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- HNF1A (HNF1 Homeobox A (HNF1A))
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别名
- HNF1A
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背景
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Synonyms: Albumin proximal factor, Hepatic nuclear factor 1 alpha, Hepatic transcription factor 1 alpha, HNF-1A, Interferon production regulator factor, LFB1, LFB1 hepatic nuclear factor, Liver specific transcription factor LFB1, Maturity onset diabetes of the young 3 (MODY3), TCF1, Transcription factor 1 hepatic
Gene Symbol: HNF1A
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分子量
- 79 kDa
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基因ID
- 6927
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UniProt
- P20823
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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