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GNAQ 抗体 (CF®647)

This anti-GNAQ antibody is a 小鼠 单克隆 antibody detecting GNAQ in . Suitable for 人.
产品编号 ABIN7654736
发货至: 中国

Quick Overview for GNAQ 抗体 (CF®647) (ABIN7654736)

抗原

See all GNAQ 抗体
GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

适用

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宿主

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小鼠

克隆类型

  • 45
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单克隆

标记

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This GNAQ antibody is conjugated to CF®647

应用范围

请咨询

克隆位点

GNAQ-2434
  • 原理

    Guanine nucleotide-binding protein alpha-q / GNAQ / G-ALPHA-q(GNAQ/2434), CF647 conjugate

    产品特性

    GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered the reading frame, multiple single based changes, and a premature termination codon in the open reading frame, all hallmarks of a processed pseudogene. Probes derived from human GNAQ cDNA sequence mapped both chromosomes 2 and 9 in higher constringency genomic blot analyses of DNA from a panel of human/rodent hybrid cell lines. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human GNAQ protein

    亚型

    IgG2b, kappa
  • 应用备注

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

    别名

    G-Alpha-q

    背景

    Synonyms: CMC1, G alpha Q, G protein alpha Q, GAQ, guanine nucleotide binding protein (G protein), q polypeptide, Guanine nucleotide-binding protein G(q) subunit alpha, SWS

    Gene Symbol: GNAQ

    分子量

    45 kDa

    基因ID

    2776

    UniProt

    P50148

    途径

    JAK/STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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