GPN1 抗体 (CF®640R)
Quick Overview for GPN1 抗体 (CF®640R) (ABIN7654647)
抗原
See all GPN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GPN1 / XAB1 (DNA Repair & Protein Synthesis) (GPN1/2350), CF640R conjugate
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产品特性
- GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human GPN1 protein
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亚型
- IgG1, kappa
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anti-GPN-Loop GTPase 1 (GPN1) (AA 9-118) antibody
GPN1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-GPN-Loop GTPase 1 (GPN1) (AA 9-119) antibodyGPN1 适用: 人 WB, ELISA, IF, IHC (p), IHC 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-GPN-Loop GTPase 1 (GPN1) (AA 1-374) antibodyGPN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-GPN-Loop GTPase 1 (GPN1) antibodyGPN1 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal GPN1-2350 unconjugated
anti-GPN-Loop GTPase 1 (GPN1) (AA 1-374) antibodyGPN1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-GPN-Loop GTPase 1 (GPN1) (AA 269-388) antibodyGPN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. ELISA: For coating order antibody without BSA. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Pancreas, Testis, Thyroid or Bladder.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- GPN1 (GPN-Loop GTPase 1 (GPN1))
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别名
- GPN1
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背景
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Synonyms: ATP(GTP) binding protein (ATPBD1A), GPN-loop GTPase 1, GPN1, MBD2-interacting protein (MBDin), NTPBP, RNA polymerase II associated protein 4 (RPAP4), XPA-binding protein 1 (XAB1) GTPase
Gene Symbol: GPN1
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分子量
- 42 kDa
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基因ID
- 11321
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UniProt
- Q9HCN4
抗原
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