Recombinant GP2 抗体 (AA 35-179) (CF®405S)
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北京 101111
Quick Overview for Recombinant GP2 抗体 (AA 35-179) (CF®405S) (ABIN7654535)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-179
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原理
- GP2 (Glycoprotein 2) / ZAP75 (GP2/2569R), CF405S conjugate
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产品特性
- GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human GP2 protein fragment (around aa35-179)
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亚型
- IgG
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anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 35-179) antibody
GP2 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal GP2-1712 unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 35-179) antibodyGP2 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal GP2-1805 unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 35-179) antibodyGP2 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal GP2-1803 unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (Middle Region) antibodyGP2 适用: 人, 小鼠, 大鼠, Cow, Pig, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 301-506) antibodyGP2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 35-179) antibodyGP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal GP2-2569R unconjugated Recombinant Antibody
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 35-179) antibodyGP2 适用: 人 IHC 宿主: 小鼠 Monoclonal 475M unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 182-231) antibodyGP2 适用: 人, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 55-84), (N-Term) antibodyGP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32338 unconjugated
anti-Glycoprotein 2 (Zymogen Granule Membrane) (GP2) (AA 35-497) antibodyGP2 适用: 小鼠, 大鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Does not react with mouse. ELISA: 2-4 μg/m for coating order Ab without BSA. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: PANC-1 cells. Pancreas
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
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别名
- GP2
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物质类
- Viral Protein
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背景
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Synonyms: Glycoprotein 2 (zymogen granule membrane), GP2, Pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
Gene Symbol: GP2
Tissue Expression: M cells
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分子量
- 59 kDa
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基因ID
- 2813
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UniProt
- P55259
抗原
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