Recombinant CD235a/GYPA 抗体
Quick Overview for Recombinant CD235a/GYPA 抗体 (ABIN7654532)
抗原
See all CD235a/GYPA (GYPA) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Glycophorin A / CD235a (Erythrocyte Marker)(GYPA/3219R)
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产品特性
- Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human GYPA protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Erythrocytes in any human tissues
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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别名
- CD235a
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背景
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Synonyms: Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha
Gene Symbol: GYPA
Tissue Expression: Red blood cells
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分子量
- 39 kDa
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基因ID
- 2993, 2994
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UniProt
- P02724
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途径
- Maintenance of Protein Location
抗原
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