GATA3 抗体 (AA 357-436) (CF®568)
Quick Overview for GATA3 抗体 (AA 357-436) (CF®568) (ABIN7654318)
抗原
See all GATA3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 357-436
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原理
- GATA-3 (Breast and Urothelial Marker)(GATA3/2445), CF568 conjugate
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产品特性
- GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas. 'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human GATA3 protein (around aa 357-436)
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亚型
- IgG1, kappa
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- GATA3 (GATA Binding Protein 3 (GATA3))
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别名
- GATA-3
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背景
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Synonyms: GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3
Gene Symbol: GATA3
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分子量
- ~50 kDa
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基因ID
- 2625
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UniProt
- P23771
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途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
抗原
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