Gastrin 抗体 (CF®647)
Quick Overview for Gastrin 抗体 (CF®647) (ABIN7654260)
抗原
See all Gastrin (GAST) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Gastrin(GAST/2635), CF647 conjugate
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产品特性
- Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human GAST protein
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亚型
- IgG1, kappa
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anti-Gastrin (GAST) (AA 1-101) antibody
GAST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (C-Term) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 77-92) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 1-101) antibodyGAST 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G5 unconjugated
anti-Gastrin (GAST) (Center) antibodyGAST 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 52-101) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 1-104) antibodyGAST 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) antibodyGAST 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal GAST-2632 unconjugated
anti-Gastrin (GAST) antibodyGAST 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal GAST-2631 unconjugated
anti-Gastrin (GAST) (AA 1-100) antibodyGAST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Human Pituitary or Stomach.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Gastrin (GAST)
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别名
- Gastrin
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背景
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Synonyms: Component II, GAS, Gast, Gastrin component I, Gastrin component II, Gastrin component III, Gastrin precursor, Gastrin-14, Gastrin-17, Gastrin-34, Gastrin-52, Gastrin-6, Gastrin-71
Gene Symbol: GAST
Tissue Expression: Pancreatic islet cells|Stomach
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分子量
- 2/4/14 kDa
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基因ID
- 2520
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UniProt
- P01350
抗原
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