我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Recombinant FOXA1 抗体 (AA 372-472) (CF®405S)

Name: Recombinant FOXA1 抗体 (AA 372-472) (CF®405S)
SKU: ABIN7654184
Availability: OutOfStock

This anti-FOXA1 antibody is a 兔单克隆 antibody detecting FOXA1 in WB, IHC, FACS, IF 和 IHC (fp). Suitable for 人和大鼠.

产品编号 ABIN7654184

发货至: 中国

Quick Overview for Recombinant FOXA1 抗体 (AA 372-472) (CF®405S) (ABIN7654184)

抗原

See all FOXA1 抗体

FOXA1 (Forkhead Box A1 (FOXA1))

抗体类型

Recombinant Antibody

适用

人, 大鼠

宿主

兔

克隆类型

单克隆

标记

This FOXA1 antibody is conjugated to CF®405S

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

FOXA1-2230R

Discover our top product FOXA1 Primary Antibody

抗原表位
45

33

12

12

8

4

4

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 372-472

原理

FOXA1 / HNF3A (FOXA1/2230R), CF405S conjugate

产品特性

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

Recombinant human FOXA1 protein fragment (around aa372-472)

亚型

IgG
anti-Forkhead Box A1 (FOXA1) (C-Term) antibody
Verified FOXA1 适用: 人, 小鼠 WB, FACS, IF, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibody
FOXA1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2D7 unconjugated

anti-Forkhead Box A1 (FOXA1) (C-Term) antibody
FOXA1 适用: 人 WB, IF, IHC (p), IP, ICC, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibody
FOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibody
FOXA1 适用: 人 WB, IHC, FACS, IF, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1512 unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibody
FOXA1 适用: 人, 大鼠 WB, IHC, StM 宿主: 小鼠 Monoclonal FOXA1-1518 unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibody
FOXA1 适用: 人, 大鼠 IHC, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1241 unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibody
FOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibody
FOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated

anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibody
FOXA1 适用: 人, 大鼠 IHC, ISt, StM 宿主: 兔 Monoclonal FOXA1-2230R unconjugated Recombinant Antibody

应用备注

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1.0 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA pH 9.0 for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

说明

Positive Control: HepG-2 or MCF-7 cells. Liver, Pancreas, Bladder, Prostate, Colon and Lung and Breast.

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Protect from light

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

FOXA1 (Forkhead Box A1 (FOXA1))

别名

FOXA1

背景

Synonyms: Forkhead box protein A1 (FOXA1), Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A), Transcription factor 3A (TCF-3A or TCF3A)
Gene Symbol: FOXA1

分子量

49 kDa

基因ID

3169

UniProt

P55317

途径

Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis