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Recombinant Filaggrin 抗体 (AA 198-288) (CF®647)

Name: Recombinant Filaggrin 抗体 (AA 198-288) (CF®647)
SKU: ABIN7654078
Availability: OutOfStock

This anti-Filaggrin antibody is a 小鼠单克隆 antibody detecting Filaggrin in IHC 和 IHC (fp). Suitable for 人.

产品编号 ABIN7654078

发货至: 中国

Quick Overview for Recombinant Filaggrin 抗体 (AA 198-288) (CF®647) (ABIN7654078)

抗原

See all Filaggrin (FLG) 抗体

Filaggrin (FLG)

抗体类型

Recombinant Antibody

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Filaggrin antibody is conjugated to CF®647

应用范围

Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

RFLG-1561

Discover our top product FLG Primary Antibody

抗原表位
38

30

8

6

4

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 198-288

原理

Filaggrin (Keratinocyte Differentiation Marker)(rFLG/1561), CF647 conjugate

产品特性

Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

Recombinant human Filaggrin protein fragment (aa 198-288)

亚型

IgG1, kappa
anti-Filaggrin (FLG) (AA 119-336) antibody
FLG 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (AA 998-1104) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1563 unconjugated

anti-Filaggrin (FLG) (AA 198-288) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1561 unconjugated

anti-Filaggrin (FLG) (AA 3838-4061) antibody
FLG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (AA 198-288) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 兔 Monoclonal FLG-1957R unconjugated Recombinant Antibody

anti-Filaggrin (FLG) (AA 198-288) antibody
FLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal rFLG-1561 unconjugated Recombinant Antibody

anti-Filaggrin (FLG) antibody
FLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (AA 3905-4031) antibody
FLG 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (pTyr654) antibody
FLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Filaggrin (FLG) (pTyr154) antibody
FLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

Positive Control: U-251-MG cells. Skin.

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Protect from light

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

Filaggrin (FLG)

别名

Filaggrin

背景

Synonyms: ATOD2, Epidermal Filaggrin, Filaggrin, Filaggrin precursor, Fillagrin, FLG, Profilaggrin
Gene Symbol: FLG

分子量

26-45 kDa (Processed), 350 kDa (Profilaggrin)

基因ID

2312

UniProt

P20930

途径

Sensory Perception of Sound, Stem Cell Maintenance