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Fibronectin 抗体 (AA 467-595) (Biotin)

This anti-Fibronectin antibody is a 小鼠 单克隆 antibody detecting Fibronectin in . Suitable for 人.
产品编号 ABIN7654061
发货至: 中国

Quick Overview for Fibronectin 抗体 (AA 467-595) (Biotin) (ABIN7654061)

抗原

See all Fibronectin 抗体
Fibronectin

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Fibronectin antibody is conjugated to Biotin

应用范围

请咨询

克隆位点

FN1-2949
  • 抗原表位

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    AA 467-595

    原理

    Fibronectin(FN1/2949), Biotin conjugate

    产品特性

    Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (around aa 467-595) of human fibronectin protein

    亚型

    IgG1, kappa
  • 应用备注

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: SW156 cells or Kidney

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Fibronectin

    背景

    Synonyms: Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3

    Gene Symbol: FN1

    分子量

    220 kDa (monomer), 440 kDa (dimer)

    基因ID

    2335

    UniProt

    P02751
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