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Fibronectin 抗体 (CF®488A)

This anti-Fibronectin antibody is a 小鼠 单克隆 antibody detecting Fibronectin in WB 和 IF. Suitable for 人.
产品编号 ABIN7654054
发货至: 中国

Quick Overview for Fibronectin 抗体 (CF®488A) (ABIN7654054)

抗原

See all Fibronectin 抗体
Fibronectin

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Fibronectin antibody is conjugated to CF®488A

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

Fn-3
  • 原理

    Fibronectin(Fn-3), CF488A conjugate

    产品特性

    Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    FR5 cells, derived by SV40 transformation of human mammary epithelial cells.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: SW156 cells. Kidney.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Fibronectin

    背景

    Synonyms: Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3

    Gene Symbol: FN1

    分子量

    220 kDa (monomer), 440 kDa (dimer)

    基因ID

    2335

    UniProt

    P02751
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