Ezrin 抗体 (CF®488A)
Quick Overview for Ezrin 抗体 (CF®488A) (ABIN7653905)
抗原
See all Ezrin (EZR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Ezrin / p81(CPTC-Ezrin-1), CF488A conjugate
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产品特性
- Ezrin, Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70 % homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length Ezrin protein
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亚型
- IgG2b, kappa
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anti-Ezrin (EZR) (AA 292-464) antibody
EZR 适用: 人, 小鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F1A9 unconjugated
anti-Ezrin (EZR) (AA 1-295) antibodyEZR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (pTyr478) antibodyEZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Ezrin (EZR) antibodyEZR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-Ezrin-1 unconjugated
anti-Ezrin (EZR) (pTyr353) antibodyEZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 350-470) antibodyEZR 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 455-586) antibodyEZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-251) antibodyEZR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: SKBr3, HeLa, HEK293, MCF-7, Jurkat, A431, MCF-7. Cerebral cortex and hippocampus.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Ezrin (EZR)
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别名
- Ezrin
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背景
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Synonyms: Villin-2, CVIL, Epididymis secretory protein Li 105, EZR, p81, VIL2, Cytovillin, Cytovillin 2, HEL S 105, DKFZp762H157
Gene Symbol: Ezrin
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分子量
- 87 kDa
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基因ID
- 7430
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UniProt
- P15311
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途径
- Maintenance of Protein Location
抗原
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