RCAS1 抗体
Quick Overview for RCAS1 抗体 (ABIN7653866)
抗原
See all RCAS1 (EBAG9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-1)
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产品特性
- EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length EBAG9 protein
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亚型
- IgG2c, kappa
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anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 1-213) antibody
EBAG9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 31-213) antibodyEBAG9 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibodyEBAG9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-EBAG9-2 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibodyEBAG9 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal CPTC-EBAG9-1 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyVerified EBAG9 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 小鸡, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 28-213) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 88-117) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal RB41813 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: MCF-7, Jurkat, 293 cell lysates, Human skeletal muscle tissue.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
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别名
- Estrogen Receptor Binding Site Associated, Antigen 9
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背景
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Synonyms: BAG9, cancer associated surface antigen, cancer associated surface antigen RCAS1, EB9, estrogen receptor binding fragment associated gene 9, PDAF, receptor binding cancer antigen expressed on SiSo cells
Gene Symbol: EBAG9
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分子量
- 32 kDa
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基因ID
- 9166
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UniProt
- O00559
抗原
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