Recombinant Elastin 抗体 (CF®740)
Quick Overview for Recombinant Elastin 抗体 (CF®740) (ABIN7653429)
抗原
See all Elastin (ELN) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis)(ELN/3131R), CF740 conjugate
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产品特性
- Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human Elastin protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Elastin (ELN)
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别名
- Elastin
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背景
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Synonyms: Elastin, ELN, SVAS, Tropoelastin, WBS, WS
Gene Symbol: ELN
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分子量
- 70 kDa
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基因ID
- 2006
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UniProt
- P15502
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途径
- Regulation of Actin Filament Polymerization
抗原
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