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Elastin 抗体 (CF®647)

This anti-Elastin antibody is a 小鼠 单克隆 antibody detecting Elastin in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7653424
发货至: 中国

Quick Overview for Elastin 抗体 (CF®647) (ABIN7653424)

抗原

See all Elastin (ELN) 抗体
Elastin (ELN)

适用

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宿主

  • 64
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小鼠

克隆类型

  • 51
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单克隆

标记

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This Elastin antibody is conjugated to CF®647

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

ELN-1981
  • 原理

    Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) (ELN/1981), CF647 conjugate

    产品特性

    Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human Elastin protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Elastin (ELN)

    别名

    Elastin

    背景

    Synonyms: Elastin, ELN, SVAS, Tropoelastin, WBS, WS

    Gene Symbol: ELN

    分子量

    70 kDa

    基因ID

    2006

    UniProt

    P15502

    途径

    Regulation of Actin Filament Polymerization
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