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DBN1 抗体 (AA 150-281)

This anti-DBN1 antibody is a 小鼠 单克隆 antibody detecting DBN1 in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7653296
发货至: 中国
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Quick Overview for DBN1 抗体 (AA 150-281) (ABIN7653296)

抗原

See all DBN1 抗体
DBN1 (Drebrin 1 (DBN1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DBN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

DBN1-2879
  • 抗原表位

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    AA 150-281

    原理

    Drebrin 1 (DBN1)(DBN1/2879)

    产品特性

    Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (aa 150-281) of human DBN1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    DBN1 (Drebrin 1 (DBN1))

    别名

    Drebrin 1

    背景

    Synonyms: Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE

    Gene Symbol: DBN1

    Tissue Expression: Heart|Skeletal Muscle|Brain|Kidney|Neurons|Pancreas|Placenta

    分子量

    120 kDa

    基因ID

    1627

    UniProt

    Q16643

    途径

    Maintenance of Protein Location
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