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Desmoglein 3 抗体 (AA 379-491) (Biotin)

Name: Desmoglein 3 抗体 (AA 379-491) (Biotin)
SKU: ABIN7653158
Availability: OutOfStock

This anti-Desmoglein 3 antibody is a 小鼠单克隆 antibody detecting Desmoglein 3 in IHC 和 IHC (fp). Suitable for 人.

产品编号 ABIN7653158

发货至: 中国

Quick Overview for Desmoglein 3 抗体 (AA 379-491) (Biotin) (ABIN7653158)

抗原

See all Desmoglein 3 (DSG3) 抗体

Desmoglein 3 (DSG3)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Desmoglein 3 antibody is conjugated to Biotin

应用范围

Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

DSG3-2838

Discover our top product DSG3 Primary Antibody

抗原表位
54

15

9

7

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4

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2

1

1

1

1

1
AA 379-491

原理

Desmoglein-3 (Squamous Cell Marker)(DSG3/2838), Biotin conjugate

产品特性

Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

Recombinant fragment (around aa 379-491) human DSG3 protein

亚型

IgG1, kappa
anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6G2C11 unconjugated

anti-Desmoglein 3 (DSG3) (AA 379-491) antibody
DSG3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DSG3-2840 unconjugated

anti-Desmoglein 3 (DSG3) (AA 858-999) antibody
DSG3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Desmoglein 3 (DSG3) (AA 379-491) antibody
DSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-543M unconjugated

anti-Desmoglein 3 (DSG3) (AA 50-75) antibody
DSG3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Desmoglein 3 (DSG3) (AA 70-615) antibody
DSG3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Desmoglein 3 (DSG3) (AA 379-491) antibody
DSG3 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal DSG3-2796 unconjugated

anti-Desmoglein 3 (DSG3) antibody
DSG3 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal 5G11 unconjugated

anti-Desmoglein 3 (DSG3) antibody
DSG3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Desmoglein 3 (DSG3) (AA 334-604) antibody
DSG3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

Desmoglein 3 (DSG3)

别名

Desmoglein-3

背景

Synonyms: 130 kDa pemphigus vulgaris antigen (PVA), Balding (Bal), Cadherin family member 6 (CDHF6), Desmoglein-3 (DSG3)
Gene Symbol: DSG3
Tissue Expression: Epidermal cells

分子量

130 kDa

基因ID

1830

UniProt

P32926