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Recombinant Chromogranin A 抗体

This anti-Chromogranin A antibody is a 小鼠 单克隆 antibody detecting Chromogranin A in IHC 和 IHC (fp). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7652438
发货至: 中国

Quick Overview for Recombinant Chromogranin A 抗体 (ABIN7652438)

抗原

See all Chromogranin A (CHGA) 抗体
Chromogranin A (CHGA)

抗体类型

Recombinant Antibody

适用

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人, 大鼠, 小鼠

宿主

  • 127
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小鼠

克隆类型

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单克隆

标记

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This Chromogranin A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

RCHGA-798
  • 原理

    Chromogranin A / CHGA (Neuroendocrine Marker) (rCHGA/798)

    产品特性

    Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human CHGA protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: PC12 cells. Adrenal gland, bowel, thyroid, pancreas, or pheochromocytoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Chromogranin A (CHGA)

    别名

    CHGA

    背景

    Synonyms: Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Pituitary Secretory Protein I, SP-I, Vasostatin I or II

    Gene Symbol: CHGA

    Tissue Expression: Neuroendocrine cells

    分子量

    68-75 kDa

    基因ID

    1113

    UniProt

    P10645

    途径

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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