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CHD4 抗体 (C-Term)

This 小鼠 单克隆 anti-CHD4 antibody (Clone 3F2-4) specifically detects CHD4 in WB, IF, IHC 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7652388
发货至: 中国
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Quick Overview for CHD4 抗体 (C-Term) (ABIN7652388)

抗原

See all CHD4 抗体
CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

适用

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  • 1
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人, 小鼠

宿主

  • 44
  • 20
  • 1
小鼠

克隆类型

  • 34
  • 31
单克隆

标记

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  • 4
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This CHD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

3F2-4
  • 抗原表位

    • 12
    • 5
    • 3
    • 2
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    • 1
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    C-Term

    原理

    CHD4(3F2/4)

    产品特性

    CHD4/Mi-2b is a component of the nucleosome remodeling and deacetylase (NuRD) complex which is a multi-subunit protein complex containing both histone deacetylase and nucleosome-dependent ATPase subunits. Current models predict that this complex function primarily in transcriptional repression. Accumulating evidence indicates that NuRD may regulate the transcription of specific genes by interacting with specific transcriptional factors. In addition, the NuRD complex may also participate in genome-wide transcriptional regulation through an association with histone tails. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Synthetic peptide (N- and C- terminal peptides were used for immunisation: 1. ASGLGSPSPCSAGSEEEDM & 2. CSRLANRAPEPPPQQVAQQQ) - which peptide the antibody recognises has not been tested.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa whole cell lysate or human placenta tissue lysate. Human breast carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, no BSA, no azide

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at -20 °C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

    别名

    CHD4

    背景

    Synonyms: ATP dependent helicase CHD4, Chromodomain helicase DNA binding protein 4, Mi 2 autoantigen 218 kDa protein, Mi 2b, Mi2 beta

    Gene Symbol: CHD4

    分子量

    238 kDa

    基因ID

    1108

    UniProt

    Q14839
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