CD8B 抗体 (CF®568)
Quick Overview for CD8B 抗体 (CF®568) (ABIN7652217)
抗原
See all CD8B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD8B (Cytotoxic / Suppressor T-Cell Marker)(CBB/1595), CF568 conjugate
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产品特性
- The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Antibody was raised against bovine CD8b.
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亚型
- IgG1, kappa
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: HuT78 or hPBL. Tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD8B (CD8b Molecule (CD8B))
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别名
- CD8b
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背景
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Synonyms: CD8 antigen 37 kDa chain, CD8 antigen, beta chain, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta polypeptide 1, CD8B, LEU2, LYT3, OX 8 membrane antigen, p37, T cell surface glycoprotein CD8 beta chain
Gene Symbol: CD8B
Tissue Expression: T-cells
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分子量
- 32 kDa
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基因ID
- 926
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UniProt
- P10966
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途径
- TCR Signaling
抗原
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