CD7 抗体 (CF®405S)
Quick Overview for CD7 抗体 (CF®405S) (ABIN7651928)
抗原
See all CD7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD7 (T-Cell Leukemia Marker)(CD7/3737), CF405S conjugate
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产品特性
- Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length CD7 protein
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亚型
- IgG2a, kappa
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anti-CD7 (CD7) (AA 26-134) antibody
CD7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 23-128) antibodyCD7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3D11F12 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-186 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B1C9 unconjugated
anti-CD7 (CD7) (AA 72-175) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 5B10E3 unconjugated
anti-CD7 (CD7) (AA 24-150) antibodyCD7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 21-240) antibodyCD7 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-007R unconjugated Recombinant Antibody
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Jurkat or Molt-4 cells. Human peripheral blood lymphocytes.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD7
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别名
- CD7
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背景
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Synonyms: GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41
Gene Symbol: CD7
Tissue Expression: NK cells|T-cells
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分子量
- 40 kDa
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基因ID
- 924
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UniProt
- P09564
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途径
- Cell-Cell Junction Organization
抗原
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