CD207 抗体 (AA 74-213)
Quick Overview for CD207 抗体 (AA 74-213) (ABIN7650972)
抗原
See all CD207 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 74-213
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原理
- Langerin / CD207 (Marker of Langerhans Cells)(LGRN/1821)
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产品特性
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa74-213) of human Langerin protein
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亚型
- IgG2a, kappa
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anti-CD207 Molecule, Langerin (CD207) (AA 155-328) antibody
CD207 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1C5A1 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 1-328) antibodyCD207 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) antibodyCD207 适用: 人, Non-Human Primate ELISA, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal LGRN-1821 unconjugated
anti-CD207 Molecule, Langerin (CD207) antibodyCD207 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 12D6 unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 161-260) antibodyCD207 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (Internal Region) antibodyCD207 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 1-328) antibodyCD207 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 ELISA, Coat 宿主: 兔 Monoclonal LGRN-3136R unconjugated Recombinant Antibody
anti-CD207 Molecule, Langerin (CD207) (AA 74-213) antibodyCD207 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal rLGRN-1821 unconjugated Recombinant Antibody
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: HeLa or A549 cells (WB).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD207 (CD207 Molecule, Langerin (CD207))
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别名
- CD207
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背景
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Synonyms: C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin
Gene Symbol: CD207
Tissue Expression: Heart|Lymph node|Dendritic cells|Liver|Lung|Spleen|Thymus
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分子量
- 48 kDa
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基因ID
- 50489
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UniProt
- Q9UJ71
抗原
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