CD2 抗体 (CF®740)
Quick Overview for CD2 抗体 (CF®740) (ABIN7650941)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD2(HuLy-m1), CF740 conjugate
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产品特性
- CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human thymocytes
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亚型
- IgG2b, kappa
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anti-CD2 (CD2) (AA 25-140) antibody
CD2 适用: 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (N-Term) antibodyCD2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人 FACS, IF, WB, Func 宿主: 小鼠 Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 FITC
anti-CD2 (CD2) antibody (PE)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 PE
anti-CD2 (CD2) antibody (FITC)GMP Grade CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal OKT11 FITC
anti-CD2 (CD2) (AA 25-209) antibodyCD2 适用: 人 IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人, Pig, Non-Human Primate FACS, IF 宿主: 小鼠 Monoclonal LFA2-600 unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: 293T or Jurkat cells. Lymph node and tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD2
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别名
- CD2
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背景
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Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11
Gene Symbol: CD2
Tissue Expression: Lymphocytes|NK cells|T-cells
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分子量
- ~50 kDa
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基因ID
- 914
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UniProt
- P06729
抗原
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